Search on: THYMINE DNA GLYCOSYLASE 
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Descriptor English:   Thymine DNA Glycosylase 
Descriptor Spanish:   Timina ADN Glicosilasa 
Descriptor Portuguese:   Timina DNA Glicosilase 
Tree Number:   D08.811.074.249.750
D08.811.277.450.430.099.750
Definition English:   An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine. 
History Note English:   2004; use THYMINE DNA GLYCOSYLASE (NM) 1991-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38128 
Unique Identifier:   D044502 

Occurrence in VHL: 		 

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